Kac Para Yarismasi

Arthritis Diet and Exercises

“Inhibiting Platelet Activation with Tomato Seeds” In the prevention of
cardiovascular disease, the consumption of fruits
and vegetables is crucial. Yes, preventing the oxidation of
cholesterol may be one of the mechanisms by which fruits and vegetables reduce
the risk of heart attacks and strokes. However, hyperactivity of platelets
is also critically important in the development of cardiovascular
disease, as I’ve covered before. In recent years, it has
been shown that platelets are not only involved in
the clotting process, but also they play an active role
in the inflammatory process of atherosclerosis
from the beginning. And that means from childhood. By the end of our teens atherosclerotic
lesions are present in most people living in
industrialized societies, and so suppressing the overactivity
of platelets may be beneficial not only for heart disease
but for cancer and allergies, and other disease for which
inflammation plays a major role.
The antioxidant properties of fruits
and veggies are well-known, however their anti-clotting effects
on platelets are less known. Preliminary studies
have demonstrated the platelet activation suppressing activity
of a variety of fruits and vegetables, so much so they can mess
up platelet function tests. And the effects are
so long-lasting, just fasting the morning of your
blood test may not be sufficient. Out of the 16 different fruits tested,
tomatoes came out #1. The anti-platelet activation components
in tomatoes are water soluble, so you don’t have to
eat them with fat, heat stable, meaning you can cook
tomatoes without losing benefits, and concentrated in the yellow
fluid around the seeds, which is why tomato pomace beat
out tomato juice, sauce or ketchup. Pomace is basically
the seeds and the peel, which the industry
throws away, and it may be the
healthiest part. And the more tomato seeds,
the better. But this was measuring platelet
activation in a petri dish. Grapefruit came
in #2 here. And grapefruit juice at least did not appear
to help when people actually drank it. So, would drinking tomato
juice actually help? Yes. Platelets of patients with diabetes
are characterized by intensified activation, so 20 diabetics were asked to drink a daily
cup of tomato juice for three weeks —or a tomato-flavored
placebo beverage and there was significant drop in platelet
activation in the real juice group. Works in healthy people too. Within 3 hours of consumption, two tomatoes
are good, but six tomatoes are better. And the effects were more wide-ranging
than those of aspirin in that the tomatoes targeted multiple
pathways of platelet activation. About 1 in 4 people are
so-called aspirin resistant, meaning aspirin doesn’t work
to calm down their platelets, whereas only 3% of study subjects
were found to be tomato resistant. This finding indicates an advantage
of the tomato extract’s broad antiplatelet activity profile over
single-target drugs such as aspirin, and when researchers stuck tubes into people
while they were eating tomatoes, they found no changes
in blood clotting time, implying that supplementation with tomatoes
should not result in prolonged bleeding times, so one might get the best of both worlds,
less platelet activation without the bleeding risk. But if tomatoes don’t thin
our blood, do they work? Consumption of tomato products has been
found to be protectively correlated with a lower incidence
of acute coronary events, less development of
early atherosclerosis, and lower mortality
from heart disease. If you don’t
like tomatoes, kiwifruit recently beat them out in a
test tube study of platelet activation. Strawberries may
help too, but we have data showing kiwis
may actually work in people too, and two kiwis appeared to work
just as well as three kiwis. It appears to work for
green-on-the-inside kiwifruit; and for yellow-on-the-inside kiwifruit. In this case, though, only one-a-day
seemed to help whereas two-a-day did not, which seems a little strange. And there haven’t been any studies
to see if kiwifruit eaters actually have fewer strokes
and heart attacks, so the best evidence for a dietary intervention
to decrease platelet activation currently rests
with tomatoes.

Leave a Reply

Your email address will not be published. Required fields are marked *