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Arthritis Diet and Exercises

Why Do Arteries Get Clogged? It’s Not What You Think


Cardiovascular disease has been the number
one killer in the world for over a decade and statistically, it’s the number one most
likely thing to kill me, so I’m definitely interested in learning more about it. It brings
to mind one phrase you may have heard now and then, “clogged arteries.” And I’m
going to be completely honest, before I got to college and learned the mechanism behind
this disease, I thought clogged arteries were a direct result of diet. Like if I put too
much butter on my potatoes, that butter was clogging my arteries. But it turns out that’s
not what happens. The term Cardiovascular disease is a catch-all for a bunch of different
diseases, and there are a ton of factors that go into what causes each kind. But the structure
we need to learn to understand these diseases isn’t the heart necessarily, it’s those
arteries. These things are complex, ever changing organs that deliver blood throughout
the body and play a role not just in disease, but in experiencing different climates, exercising,
and maintaining homeostasis. In the last few videos, we’ve been talking about the components of blood, which includes a bunch of specialized cells. We’ve got red blood cells for carrying
and delivering oxygen to hungry body parts, and the white blood cells that make up a big
part of our immune system. But we haven’t talked about the hardware that contains them
and moves them. That’s where the cardiovascular system comes in. If you prefer calling it
the circulatory system, that’s fine too — they’re the same thing. In this video,
I’ll use cardiovascular because the name gives away its pieces: the heart, hence the
cardio portion, and all the blood vessels, which is the vascular part. Now, the heart
is an incredibly complex organ and we could dedicate an entire series to it, but for now,
we’re going to focus on the blood vessels, those tubelike structures that transport blood
around the body. When you take a big picture look at the cardiovascular system, you’ll
notice two distinct loops of blood vessel networks, like a figure eight. One of those
loops carries deoxygenated blood from the right side of the heart to the lungs, picks
up some oxygen, and circles back to the heart. This loop’s pretty straightforward, only
one organ to visit. This pulmonary circulation is where important gas exchange happens, letting
us do something with all the carbon dioxide waste we’ve built up in our blood and capture
that oxygen we breathe in. Once our blood is nice and oxygenated it comes back to the
left side of the heart to be pumped into systemic circulation, the loop that hits everything
that isn’t the lungs. As you can imagine from the everything about this, the systemic
circulation has a little more going on. Right after getting ejected from the left side of
the heart, blood passes through the aorta, the biggest artery we have. This artery is
going to branch off into smaller arteries up into the neck and brain and down the body
into the limbs and abdomen. As they get closer to individual tissues and organs, they’ll
branch off into tiny arterioles, and then into microscopic blood vessels called capillaries.
Some of those capillaries are so tiny that red blood cells have to line up cell by cell
to get through. Not all of our arteries are built the same. Big arteries close to
the heart, like the aorta are under a lot of pressure. And I don’t mean their parents
are hovering over their shoulder checking their math homework, I mean physical pressure
from the pumping heart muscle. To cope with this pressure, they’re built to be more
elastic, letting them expand along with the pressure. As we get to the arteries of the
arms and legs, we see them become more muscular, giving them more control of their diameter.
This is where we start seeing the arteries as more than just static tubes. An artery
itself has three main layers, or tunics: the tunica externa, media, and intima. Literally
the outer, middle, and inner layers of the artery. They all serve a different purpose,
and they all come up again in understanding cardiovascular disease. The tunica externa,
also called the adventitia, gives the artery its general shape and structure. The tunica
media is built of a protein called elastin, which, as you could tell by the name, gives
the artery some elasticity. But it’s also got a layer of contractible muscle around
it. Now, this is a different type of muscle from the skeletal muscles in your arms and
legs. This smooth muscle surrounds the entire blood vessel which provides a little more
support, but more importantly, it regulates how wide the artery becomes. Why is this so
important? Well, the ability to shrink or expand our blood vessels comes in handy in
different situations. Let’s take a look at exercise for example. Right now, you’re
at rest. Your heart is probably beating nice and steady — around sixty to a hundred beats
per minute. At that rate, about five liters of blood will pump out of your heart in the
next sixty seconds. That’s enough to feed all of your oxygen-hungry tissues at rest,
but they get hungrier when you exercise. So in order to ship more oxygen to those tissues,
your body increases its heart rate, or how frequently your heart pumps, and stroke volume,
the amount of blood squeezed out with each pump. For most of us, that means the five
liters of blood we were pumping every minute at rest can get up to thirteen liters a minute
at peak exercise, and even more if you’re a trained athlete. That means your arteries
have to adjust for two and half times more blood volume coming through. They do so by
vasodilating — the smooth muscle of the tunica media relaxes, which expands the diameter
inside the blood vessel. In a totally different situation, your arteries can vasoconstrict
as a way to reduce loss of body heat and stay warm in cold temperatures. Those changes in
diameter are all possible thanks to the tunica media, but there’s still one more layer
to arteries. The innermost layer, or tunica interna, has a little more smooth muscle and
elastin, but most importantly, it’s lined with super smooth endothelial cells. These
cells have a very important job — provide a low friction surface and make sure blood
gets through circulation as smoothly and efficiently as possible. So all in all these arteries
have a thick outer layer, a smooth inner layer, and a middle layer that changes the diameter
of the vessel, which is amazingly useful. All of this sets us up to understand how we
can go from a free flowing, smooth blood vessel to a “clogged artery”. Okay, so this process
isn’t something that happens all at once. Arteriosclerosis is the buildup of plaque
within an artery to the point where it interferes with normal function, and it can happen in
any artery. Some of these conditions get names with a little more pizazz though, a
little more oomph where you’re like “ohh dang, I don’t want that” but the pathogenesis
is the same. Like when the arteries to the brain get blocked, we call that a stroke or
when the arteries to the heart muscle get blocked we call that a heart attack. And when
those organs don’t get blood, they don’t get oxygen, and that can cause severe damage
or sometimes death. There are a few different ways it can begin, but at some point, the
endothelial cells become dysfunctional. Remember from earlier, this layer’s job is to be
as smooth as possible so blood can just flow through. And a bunch of different factors
make this condition more likely — smoking, high blood pressure, diabetes all predispose
an artery to endothelial dysfunction. For instance, smoking reduces the availability
of nitric oxide, a chemical that allows the blood vessels to vasodilate, and increases
some inflammatory factors that make the blockage even worse. But no matter what causes the
dysfunction, now the endothelium lets lipids from the blood sneak under that layer of endothelial
cells and into the intima. That starts a process where immune cells are called to the scene,
where they enter the intima and oxidize those lipids into foam cells. Foam cells sound cute,
but these things are serious. Those immune cells also recruit more smooth muscle to the
area, as well as the tough connective tissue collagen, which is definitely not supposed
to be there. As a result, instead of a soft bump you’ve got a tough, fibrous plaque.
That cycle of plaque stacking can continue until blood can barely get through an artery
and that’s when the tissues it supplies oxygen to really start to suffer. So again,
clogged arteries are the narrowing of arteries from plaque buildup and not some kind of buttery
cholesterol fatberg in your blood vessels. But that doesn’t mean it’s not dangerous. That plaque can break open, which means now there’s a blood clot free floating in your arteries.
That’s why a narrowing of the arteries around the heart is so deadly. If that loose blood
clot gets stuck on some plaque in those arteries, oxygen can’t get to the heart muscle itself
and it can die off. And that’s a heart attack. This is one of the reasons why healthcare
professionals recommend exercise for preventing heart disease. It has the ability to reduce
chronically high blood pressure and lower bad cholesterol, but it also improves your
ability to produce nitric oxide, that vasodilator that improves blood flow. One of the other
benefits of exercise is making more red blood cells, but how does that happen? Tune in to
the next episode in our playlist to find out how. I’m Patrick Kelly, thanks for watching
Seeker.

100 thoughts on “Why Do Arteries Get Clogged? It’s Not What You Think

  1. Hi Seekers, thanks for watching! Want to learn more about the human body? Check out this video on all the different blood types: https://youtu.be/Ti3Ig6b7T1g

  2. "it's not the diet"
    ….sure eat butter and not nitric oxide foods like beets and leafy greens, and if you survive tell me how it goes in a few years

  3. This needs to be so much higher. Commenting so the algorithm knows I’m interacting with this video and it should share it more

  4. Coming from a family with 2 cardiologists, I’m finding this series really interesting and well done 👍

    Of course doctors are used to patients wanting them to tell them the ultimate secret to keep them alive for 200 years. Not possible. No miraculous single generic solution. Yet.

    Catch the details in the series, make an effort to comply according to healthy habits, try to live in non polluted areas, exercise frequently, eat healthy non processed food, don’t smoke, etc. The basics. Don’t jump into trends. It usually is expensive in all aspects. Keep it simple.

    Listen to your doctor. Ask for a second opinion. Doctors only! Be smart! F1 races aren’t won with sorcery, planes don’t fly because crooks like mediums say so. It’s science. Science supports it all. And it’s hard. Be smart!

    Scientific studies from credible sources are what we have of most value to drive us into maintaining good health.

    The heart ❤️ is amazingly complex. Science keeps learning.

    Lot’s of factors contribute to our health but don’t forget we are all different (each born with a unique fingerprint). Your DNA 🧬 is unique so the timer started when you were born. Don’t let external factors accelerate the clock.

    Just some thoughts 🤷‍♂️

  5. Hahaha. OMG, diet is the biggest cause of this! You listed the smaller causes and said no matter what causes it. Butter will clog them of course, it raises the cholesterol. It almost seems like this video was designed to remove the blame from diet.

  6. So does this all mean that nitric oxide 'supplements' or similar could 'cure' heart disease?
    Like seriously I want to know. I don't want to die.

  7. im super picky about what I watch, and this is a new guy on a channel I've watched for some time now. I don't hate it. you're very good at not overdoing it. (like TKOR girl) im interested 🙂

  8. For helping sove that problem EAT RESVERATROL ( the better one is TRANSRESVERATROL = found in purple grape),
    ASTRAGALUS,
    VITAMIN K2 (IT take the calcium form around arteriosclerosis= glogged arteries)

  9. So, if I was uneducated on the topic beforehand, THIS video would have convinced me that eating with no concern for harmful intakes of saturated fats and cholesterol wouldn't make a hair's worth of difference to my arterial health. Lmao.

  10. The ancients were clogging their arteries millennia ago. It's called inflammation. Exercise, sweating, helps flush the toxins from your cells.

    "Any sufficiently advanced technology is indistinguishable from magic." – Arthur C. Clarke https://en.wikipedia.org/wiki/Clarke's_three_laws

    The purpose and meaning of tool-using monkey life is to expand human liberty and teach the concept of natural rights without which we will always be considered livestock by our would-be masters. But our schools and churches which were built for control consistently raise children to be children because they make better tools.
    amerikan evangelicals are indoctrinated in the ignorance that tells them the world will end in their lifetimes and have no conception of passing a better(FREE) world on to their own children.
    The problem is the nature of the tool-using monkeys, not what god they chose to bow down to. Rome didn't lose its republic and later its empire because they prayed to the wrong gods. Their men lost the resolve to keep them.

    Ignorance/simple answers to complex issues is/are always easier. That's what's kept the churches in business all these years. It eliminates the believers' desire, if they had any at all, to take on personal responsibility for the world they exist in.

    Religion like democracy is another control device. Be a good slave and you'll have paradise in the next life. Millions of morons wasting their time here waiting for the world to end while believing 'it's all foretold and we can't do anything about it' is a major part of the problem and one of the elites' best tools for control. It was probably designed that way.

    The crazies won't be helped by the culture war. Waking up is hard to do: http://www.freekentucky.com/waking-up-is-hard-to-do/

    The purposes of gods and golden rules http://www.freekentucky.com/the-purposes-of-gods-and-golden-rules/

    Choosing Sides: http://www.freekentucky.com/8437-2/

    What to teach your kids http://www.freekentucky.com/what-to-teach-your-kids/

    A few things that might matter: http://www.freekentucky.com/a-few-things-that-might-matter-or-the-basics-part-two/

    Why choose one version of authoritarianism over another?

    It's time for a global Bill of Rights http://www.freekentucky.com/no-sacred-cows-or-a-new-global-bill-of-rights/

    We can send the sacred, or scared, cows to Australia

    The most important things to do: http://www.freekentucky.com/the-most-important-things-to-do/

    A conspiracy to indoctrinate, or “What is an education?”: http://www.freekentucky.com/a-conspiracy-to-indoctrinate-or-what-is-an-education/

    What’s the ultimate question?: www.freekentucky.com/whats-the-ultimate-question/

    Christian rebels and modern cowards: http://www.freekentucky.com/christian-rebels-and-modern-cowards/

  11. And I wouldn't be surprised if living in a society with gas powered producing CO2 cars did the same thing to us as smoking, and also has potential to hurt the eyes and cause eye problems

  12. people who already knew all the basics of the cardiovascular system just wasted time watching this. The question isn't even answered, this isn't right. unsubscribed.

  13. Butter still does clogg your arteries, it's a freaking processed food high in saturated fat and cholesterol it will raise your serum cholesterol

  14. I don't even know what terrifies me the most, the fact that this kind of death is very painful and inevitable or that the narrator speaks about it with a positive attitude…

  15. Blah blah blah! Why don’t you answer the question that you click baited as your title I’m six minutes in you still haven’t said one word about why our arteries get clogged I’m out of here never watching this damn channel again! And watch with all the cutie pie statements he made my god so tired of these guys trying to be whatever The hell they’re trying to be just answer the damn question good grief!

  16. Dr Esseltyn and Dr McDougall have both treated patients specifically with diet having an enormous success rate with cardiovascular disease – specifically atherosclerosis …. I wouldn't be so quick to dismiss foods

  17. I have an Abdominal Aortic Dissection that descends into the left Iliac, and it is also an Aneurysm. That's probably how I will die.

  18. I wonder why the heart is designed as a two way (in/out) system and not a one way path. It takes energy to move the blood back and forth. I also don't understand why there is only one central pump. This makes the system less robust compared to distributed pumping

  19. Watching this after watching the Wired NASA Flight Surgeon video. If you haven’t watched it, go watch it now! It complements this video well.

  20. This was an okay video but I appreciate the introduction or teaser trailer to a more complex explanation. My mother had PAD and I would like to know more about that, she's healthy, and exercises frequently. Can you guys get into more detail? Cause I love the images and infographics you offer!

  21. Great video and I thank you for that. But you can lose the background music, it was annoying. Other than that I learned a lot.

  22. Currently in my city due to political police and governmental corruption we are immersed in a pandemic of addictions, if the governments do not support us it is the individuals who have to put letters in the matter, it would be nice to explain with 3D graphics and your great capacity with narrative to explain cliearlly the damage caused by all drugs, put a section Human drugs and also the correct way to get out of them.

  23. I know that Drugs is a pandemic world wide and jorunalism the media hides it, goberments make big business with it and it is a worldwide problem even worse than global warming. Medical and sicological solutions.

  24. The title is indeed misleading. Here is the definitive reason for clogged arteries.
    https://www.youtube.com/watch?v=UCBmb98vaDU

  25. The bigger question is why don't doctors check high risk patients for issues. I would imagine we have pretty good imaging tech that could spot issues before they cause serious problems.

  26. It’s well known that it’s damaged artery which allows blood congestion,those holes and cracks in those artery gets clogged with waxy cholesterol and fats,like a gardening hose that has been sun damaged with rigidity,hardened and cracked,free radicals damages from chemical especially Chlorine in our water,swimming pool and pesticides in our foods,Young American Soldiers fighting during the 50s North Korean’s war drinks lots of Chlorinated water dies of strokes and heart attacks.

  27. Literally the most useless video! No one will tell you that animal products and dairy are the biggest causative agents of clogged arteries..

  28. CAUTION CONTACT YOUR DOCTOR BEFORE YOU TRY THIS. It is amazing that fairly easy steps to help take care of the circulatory system. Personally, I like to soak in water as hot as I can tolerate for just 5 minutes. Quickly dry off and lay on the bed. At this piont I can feel all my vains open up. For me, it flushes out vains of anything that is stuck. I only do this twice a year. Medical ultrasound has confirmed the outcome for me. AS STATED AT THE BEGINNING TALK TO YOUR DR. FIRST. What works for me may be dangerous for you. Blessings and love. Stay safe.

  29. Here are some important clues on this page for your further research about plaque redux. CRP and Homocystene are some more key words and clues. The ability of certain vitamins to stop the plaque process seem to be key. https://www.cooperinstitute.org/vitamins

  30. WTF…. 98% of this video had absolutely nothing to do with why arteries get clogged… and you never answered the question! Its like asking who built the empire state building and then making a 10 minute video on how skyscrapers are built.

  31. Learn all this if you wish. It does no harm as well as no good. The real trick is how to stop this from ever happening. In Canada we have done this a long time ago. It is a licensed herbal called "Heart Drops". It can be bought in most health food stores. I had heart problems at 47 and started on this product then. Shake the bottle and then put 30 drops from the eye dropper top into a teaspoon, put it under your tongue for a few seconds then wash it down with pure water. Do this twice per day and all this goes away. Oh by the way I was playing hockey with my grandson at Christmas and I am 70 years old now, and have had no heart problems since two months after starting heart drops at 47. I still have perfect cardio health directly because of the totally clean circulatory passage ways re-established through the use of this product. Heart Drops alone stop over 90% of all forms of heart attack and all almost eliminate stroke altogether if taken as a preventative. If you wish to know if your in need of a bottle of this product do a simple test. Go to an office or apartment and go up two flights of stairs one step at a time as quickly as you can safely. Keep he same pace on the landing. As soon as you get to the top look at your watch. If your breathing does not come back to normal in 90 seconds, two min max you need heart drops. That is all you ever need to know to live in great cardio health in Canada.
    . www.Straussherbco.com.

  32. Thanks for the video! It was super informative. That said, the titles is misleading. This video explains HOW arteries get blocked. Not WHY they get blocked. Why implies that you explaining the cause of blocked arteries. There was never a reason given to as why plaque builds up in arteries.

  33. If anyone wants to get their head out of the sand of dietary cholesterol denial and see the mechanisms backed by studies, search my vid: "High Cholesterol Doesn't Cause Heart Disease | Debunked"

    I haven't even shared on of my videos in a comment in like a year and while I appreciated the anatomy points in this video the notion that the food you eat doesn't play a role is actually highly irresponsible.

  34. Atherosclerosis, a specific type of arteriosclerosis occurs when the apo-b (apolipoprotien b) biomarker is knocked off of a LDL (L1 or L2) molecule. As long as the biomarker remains your liver will recognize the LDL and recycle it. This is good because this is how you mobilize fat to be used for energy. Once it is removed the liver does not recognize it and the only place that will accept it the arterial wall. The good LDL (L1 and L2) have now become oxidized and can be either L3-L7. The 2 causes of this that I am aware of are vegetable/seed oils and carbohydrates. If your doctor wants to do a total LDL test tell him/her to do a fractionated LDL test. You want L1 and L2 to be high but L3-L7 to be as low as possible. I dont have specific sourves for this bookmarked but I have heard this information from Dr Ken Berry, Dr Rhonda Patrick and Dr Jason Fung just to name a few. Check out the youtube channel Low Carb Down Under if this information is something you care about.
    Here are 2 videos that I happen to have bookmarked that show how saturated fat does not cause an increase in oxidized LDL (L3-L7) about 30 minutes each if you're interested. Very interesting stuff.

    https://www.youtube.com/watch?v=TRB0jOfymLk

    Dr. Paul Mason – 'High cholesterol on a ketogenic diet (plus do statins work?)

    https://www.youtube.com/watch?v=NUY_SDhxf4k

    Dr. Paul Mason – 'Saturated fat is not dangerous'

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